[摘要] 目的 研究青蒿鳖甲汤联合少量激素治疗狼疮性肾炎的临床疗效。 方法 62例狼疮性肾炎患者均来至我院中医科及血液科门诊及住院部，按就诊顺序将其随机分为治疗组（32例）和对照组（30例）。治疗组口服青蒿鳖甲汤联合少量激素；对照组口服强的松片。 结果 治疗组总有效率为90.6%，对照组总有效率为66.7%，治疗组总有效率高于对照组（P ＜ 0.05）；经过观察，发现在临床症状、激素撤减情况及药物副作用方面，治疗组明显优于对照组（P ＜ 0.05）。 结论 运用青蒿鳖甲汤联合少量激素治疗狼疮性肾炎，可明显缓解临床症状，改善实验室指标，减少激素用量，稳定病情和减少西药的副作用。
[关键词] 青蒿鳖甲汤；狼疮性肾炎；强的松
[] A[文章编号] 1673-7210（2012）08（b）-0112-02
Clinical observation on Qinghao Biejia Decoction combined with a all amount of hormone in the treatment of lupus nephritis
WANG Zhihua DAI Zhaoyan QOAN Yaohua TU Yun
Zhanjiang Central people's hospital, Guangdong Province, Zhanjiang 524037, China
[Abstract] Objective To observe the clinical efficacy of Qinghao Biejia Decoction combined with a all amount of hormone in the treatment of lupus nephritis. Methods 62 patients with lupus nephritis were coming to our traditional Chinese Medicine and department of hematology in out-patient and in-patient department, were divided into two groups by visiting the order randomly, the treatment group of 32 cases and the control group of 30 cases. The treatment group were treated with Qinghao Biejia Decoction combined with a all amount of hormone; Th源于：论文范例www.808so.com
e control group were treated with Prednisone. Results The total effective rate of the treatment group was 90.6%, the total effective rate of the control group was 66.7%, the total effective rate of the teatment group was higher than that of the control group (P < 0.05); after the observation, it was found that in clinical symptoms, hrmone reduction and drug side effects, the treatment group was significantly better than the control group (P ＜ 0.05). Conclusion Using Qinghao Biejia Decoction with a all amount of hormone to treat lupus nephritis, can reduce clinical symptoms, improve laboratory parameters, reduce hormone dosage, stabilize cndition and reduce the side effects of Western medicine.
[Key words] Qinghaobiejia decoction; Lupus nephritis; Prednisone
系统性红斑狼疮（systemic lupus erythematosus，SLE）是一种多系统损害，伴有多种自身抗体形成的免疫系统疾病，肾脏是常见受累器官，狼疮性肾炎（lupus nephritis，LN）是免疫复合物沉淀引起的免疫性肾炎，笔者在临床中运用青蒿鳖甲汤加减联合少量激素治疗狼疮性肾炎，取得较好临床疗效，现报道结果如下：
1 资料与方法
1.1 一般资料
62例狼疮性肾炎患者均来自我院中医科及血液科门诊及住院部，按就诊顺序随机分为两组。治疗组32例，男5例，女27例，男女比例1∶5.4，平均年龄（31.38±10.85）岁，平均病程（2.70±0.58）年；对照组30例，男6例，女24例，男女比例1∶4，平均年龄（27.89±10.11）岁，平均病程（2.69±0.54）年。两组一般资料比较差异无统计学意义（P ＞ 0.05），具有可比性。
1.2 治疗方法
1.2.1 治疗组给予青蒿鳖甲汤联合少量激素治疗。青蒿鳖甲汤：青蒿10 g、鳖甲20 g、生地15 g、知母15 g、丹皮12 g。临症加减：气虚者加黄芪25 g、党参20 g；阴虚肠燥者加玄参15 g；阳虚者加肉苁蓉20 g、干姜9 g。激素：起始量为0.25～0.75 mg/kg每天，维持量为每日5～10 mg；4周为1个疗程，连续服用3个疗程摘自：毕业论文题目www.808so.com
dividedintotwogroupsbyvisitingtheorderrandomly,thetreatmentgroupof32casesandthecontrolgroupof30cases.ThetreatmentgroupweretreatedwithQinghaoBiejiaDecoctioncombinedwithaallamountofhormone;Th源于：论文范例www.808so.comecontrolgroupweretreatedwithPrednis WWw.808so.com 808论文查重
青蒿鳖甲汤联合少量激素治疗狼疮性肾炎疗效观察
更新时间：2024-02-28
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